- The Complete Research Material is averagely 52 pages long and it is in Ms Word Format, it has 1-5 Chapters.
- Major Attributes are Abstract, All Chapters, Figures, Appendix, References.
- Study Level: BTech, BSc, BEng, BA, HND, ND or NCE.
- Full Access Fee: ₦6,000
Get the complete project »
ABSTRACT78This research investigated the phytochemical and anti-inflammatory properties of methanol extract of Crateva adansonii stem bark. Although several edible and non-edible plants parts are used in inflammatory treatment, many record has been found of the use of Crateva adansonii stem bark. For this research, fresh stem bark of Crateva adansonii were collected from Asata village in Enugu State. The cuttings were authenticated at the Bioresource development centre. They were then dried at room temperature for one month in an open lab space, grounded into powder and weighed on a beam balance as 460.6g. The powder was soaked for twenty-four to fourty-eight hours in methanol to get a methanol extract and then concentrated into paste at a set temperature range of 30-550C in a water bath. A population of twenty adult wistar Albino rats was used for anti-inflammatory test. The rats were divided into five (5) groups of four (4) albino rats each. They were administered 3% tween-80 mixed with dichloromethane extract of Crateva adansonii and the control was administered with 0.5ml of 3% tween-80. Acute inflammation was induced an hour after test substances were administered by injecting egg albumin in the subplanter region of the right hind paw and edema assessed by mercury displacement for a period of 0-180 minutes. Anti-inflammatory effect was significant within 30 minutes of induced edema with inhibition occurring in three phases of 0-30, 30-60, 60-90. 90-120 to 180 minutes. Inhibition was highest at the third phase. Crateva adansonii barks showed anti-inflammatory effect by inhibiting “prostaglandin” synthesis an inflammatory mediatorCHAPTER ONE
1.0 INTRODUCTION
Inflation is a Latin word (inflammare) which is translated means to set on fire. It is a complex biological response of vascular tissue to harmful stimuli such as pathogens, damaged cells irritant. Inflammation is the reaction of vascularized tissue to local injury caused by certain stimuli like infections, chemicals and biochemical agents, thermal or other physical trauma, antigen-antibody interaction etc (Carol, 1994). Without inflammatory response, wounds will not heal and minor infections would be over weening. Though inflammation aims at limiting damage and restoring function, some enzymes and toxic products within phagocytic cells are released to the extend of damaging the tissue. The advent of anti-inflammatory agents has made inflammation which as been a threat to human life due to its complex, multicontent, to loose its power. These anti-inflammatory agents or drugs help reduce, pain by inhibiting inflammation as opposed to opioids, which affects the central nervous system. It also prevent repairs, prevent and stop the consequences of inflammation by acting on the body responses without directly antagonizing the causative agent (Stedman, 2000). These anti-inflammatory process involves the process of balancing pro-inflammatory acute-phase reactants (Russell et al. 2000), altering biochemical pathway78forming prostaglandins by inhibiting cyclooxygenase enzyme from catalyzing the reaction, as a result, suppress, compensate and correct the mechanical and structural abnormalities by assistive device. (Masumoto et al.2009).The inflammatory reaction is phylogenetically and ontogenetically the oldest defense mechanism. The cells of immune system are widely distributed throughout the body, but if an infection or tissue damage occurs. It is necessary to concentrate them and their products at the site of damage.
You either get what you want or your money back. T&C Apply
You can find more project topics easily, just search
-
SIMILAR BIOCHEMISTRY FINAL YEAR PROJECT RESEARCH TOPICS
-
1. SCREENING SOME MEDICINAL PLANTS AGAINST MOROCCAN WATERMELON MOSAIC VIRUS (MWMV)
» ABSTRACT The antiviral activities of plant leaves extract of four species, were investigated. The extract were tested for antiviral activities on the ...Continue Reading »Item Type & Format: Project Material - Ms Word | 50 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
2. ANALYSIS OF SOME MINERAL CONTENTS OF COCONUT WATER
» CHAPTER ONE INTPDUCTION Background of the Study The coconut (Cocos nucifera L.) is a tropical plant which belongs to the order Arecales and family Are...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
3. THE EFFECT OF KAKA BITTERS ON THE LIPID PROFILE OFWISTAR RATS FED WITH HIGH FAT DIET
» ABSTRACT Kaka bitters like other bitters is claimed to possess a number of folkloric therapeutic effects including lipid lowering effects. However, th...Continue Reading »Item Type & Format: Project Material - Ms Word | 85 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
4. COMPARATIVE QUANTITATIVE PHYTOCHEMICAL ANALYSIS OF ETHANOL EXTRACT OF Gongronema latifolium AND Allium sativum
» TABLE OF CONTENTS Cover page Title page Certification i Dedication ii Acknowledgement iii Abstract iv Table of content V List of tables vi CHAPTER ONE...Continue Reading »Item Type & Format: Project Material - Ms Word | 44 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
5. BIOCHEMISTRY OF GOUT
» CHAPTER ONE INTRODUCTION 1.1 Introduction Gout was described by Hippocrates as “the disease of kings” due to its association with rich diet. (Fala...Continue Reading »Item Type & Format: Project Material - Ms Word | 31 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
6. NUTRIGENOMICS
» CHAPTER ONE INTRODUCTION The etiology of complex chronic diseases involves both environmental and genetic factors, with environmental influences such ...Continue Reading »Item Type & Format: Project Material - Ms Word | 58 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
7. COMPARATIVE ANALYSIS OF VITAMIN C (ASCORBIC ACID) IN PINEAPPLE AND BANANA
» INTRODUCTION 1.1 HISTORICAL BACK GROUND Antibiotics are chemicals when the chemical are put into the body; they stop the growth of kinds of germs. The...Continue Reading »Item Type & Format: Project Material - Ms Word | 38 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
8. PHYTOCHEMICAL ANALYSIS OF SELECTED TOMATO PRODUCTS
» CHAPTER ONE 1.0 INTRODUCTION Intake of tomato and tomato based products contributes to the absorption of a wide range of carotenoids in human serum an...Continue Reading »Item Type & Format: Project Material - Ms Word | 74 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
9. MODULATORY EFFECT OF ETHANOLIC LEAF EXTRACT OF SPHENOCENTRUM JOLLYANUM PIERRE (SPJ) ON LIVER FUNCTION AND HAEMATOLOGICAL INDICES OF CADMIUM CHLORIDE-I...
» ABSTRACT The effect of ethanolic leaf extract of Sphenocentrum jollyanum pierre (SPJ) on liver function and hematological indices of cadmium chloride ...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
10. EVALUATION OF NUTRITIVE AND NON-NUTRITIVE COMPONENTS AND ANTI-DIABETIC PROPERTIES OF EDIBLE PORTIONS OF Chrysophyllum albidum FRUIT IN STREPTOZOTOCIN-...
» CHAPTER ONE INTRODUCTION 1.1 Background to the Study Dietary control is vital in the management of diabetes. Reports from FAO (1998); WHO and FAO (200...Continue Reading »Item Type & Format: Project Material - Ms Word | 225 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT