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ABSTRACT
Kola bark extract have been widely used in tradition medicine for
thousand of year, it improves liver functions and provides protection
against high fat fed metabolic rats. Present investigations were carried
out on the hepatoprotective role of Kola bark extract meal treatment to
high fat fed wistar rat. Healthy adult male wistar rats were divided
into four groups Group I: rats were fed a standard Laboratory diet
(groups match) (20g/rat/day), Group II: rats were fed a high-fat diet
alone (3.6g/rat/day), Group III: rats were fed with combined mixture of
70% of high-fat diet with 30% Kola bark meal (9.8g/rat /day), Group/ V:
rats were fed with high fat diet and was administered with Lipitor
(Atovastatin) (10mg/rat/day) . The rats were sacrificed at the end of
the experiment (two weeks) period. The high fat fed rat substantially
elevated its serum and liver tissue AST, ALT, ALP, bilirubin with
decreased in total protein levels. Where as the levels of all parameters
significantly restored towards normalization by the kola bark husk meal
treatment. The results obtained suggest that the Kola bark meal have
potent hepatoprotective action on high fat fed rats. A companion of the
performance in both Kola bark meal and Lipitor treatment on high fat fed
rat in respect of hepatoprotective role is clearly indicator that the
Kola bark meal treatment was more and related to the result of Lipitor
as well as to the normal level.
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SIMILAR BIOCHEMISTRY FINAL YEAR PROJECT RESEARCH TOPICS
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1. Garcinia kola Heckel STEM BARK ETHANOLIC EXTRACT AND ITS TRITERPENOID FRACTION PROTECTED AGAINST SODIUM ARSENITE-INDUCED HEPATOTOXICITY AND NEPHROTOXI...
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2. EFFECTS OF ETHANOLIC ROOT EXTRACT OF UGU OYIBO (Jatropha tanjorensis) ON HAEMATOLOGICAL INDICES OF FEMALE ALBINO WISTAR RAT
» ABSTRACT Jatropha tanjorensis is a natural medicinal herb which has been used over the years in the treatment of many health disorders. This study was...Continue Reading »Item Type & Format: Project Material - Ms Word | 76 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
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3. ANTISICKLING EFFECT AND ACTIVITY GUIDED FRACTIONATION OF DICHROSTACHYS CINEREA (Wight & Arn) ROOT AND STERCULIA SETIGERA (Del) LEAF METHANOLIC EXTRA...
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4. EFFECT OF ETHANOL LEAF EXTRACT OF Vernonia Amygdalina ON THEOBROMINE INDUCED RENAL TOXICITY IN MALE WISTAR RATS
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5. EFFECTS OF ETHANOLIC ROOT EXTRACT OF Jatropha tanjorensis ON LIPID PROFILE OF FEMALE ALBINO WISTAR RAT
» ABSTRACT This research work was carried out to determine the effects of ethanolic root extract of Jatropha tanjorensis on lipid profile of female albi...Continue Reading »Item Type & Format: Project Material - Ms Word | 62 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
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6. AN ASSESSMENT OF TEACHERS’ KNOWLEDGE OF TEST CONSTRUCTION PROCEDURE IN CHEMISTRY OBJECTIVE TEST IN SENIOR SECONDARY SCHOOLS
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7. EFFECTS OF ETHANOL ROOTS EXTRACT OF UGU OYIBO (Jatropha tanjorensis) ON HAEMATOLOGICAL INDICES OF FEMALE ALBINO WISTAR RATS
» ABSTRACT Jatropha tanjorensis is a natural medicinal herb which has been used over the years in the treatment of many health disorders. This study was...Continue Reading »Item Type & Format: Project Material - Ms Word | 82 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
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8. ANTI-SCHIZOPHRENIC EFFECT OF METHANOL LEAVE EXTRACT OF INDIGOFERA ARRECTA IN ALBINO MICE
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10. COMPARATIVE STUDY OF THE EFFECTS OF ETHANOL LEAVES AND STEM EXTRACTS OF Jatropha tanjorensis (Hospital Too Far) ON SOME LIVER FUNCTIONS OF MALE ALBINO...
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